Articles Tagged With:
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Many Ethics Committees Are Not Following AAP Guidance
In a survey of ethics consultant leaders at children’s hospitals, researchers found multiple practice gaps, including training needs; informing staff, patients, and family about ethics services; and scope of ethics service. These practice gaps could erode ethics quality and narrow ethics reach.
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New Ethical Guidance on Pediatric Decision-Making
According to the recommendations, ethical decision-making can factor in parents’ consideration of the child’s non-health interests (e.g., a child’s interest in playing football, even if it risks concussions), and also may consider the interests of other family members, provided those do not severely compromise the child’s health.
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Canakinumab Injection (Ilaris)
Canakinumab can be prescribed to adults with gout in whom nonsteroidal anti-inflammatory drugs and colchicine are contraindicated, are not tolerated, or do not provide an adequate response, and in whom repeated courses of corticosteroids are not appropriate.
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An RNA Shot for Hypertension?
One dose of a new RNA-based drug administered by subcutaneous injection, which blocks hepatic angiotensinogen production, resulted in sustained reductions in blood pressure in patients with hypertension for up to 24 weeks without any serious adverse effects.
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Is the Combination of a GLP-1 Agonist and a SGLT2 Inhibitor Safe?
An analysis of the Harmony Outcomes study and a meta-analysis combining it with the AMPLITUDE-O study of the addition of a glucagon-like peptide 1 receptor agonist (GLP-1 RA) in a subgroup of type 2 diabetes patients on baseline sodium-glucose cotransporter-2 (SGLT2) inhibitor therapy has shown that major adverse cardiovascular events are reduced by GLP-1 RA, regardless of baseline SGLT2 use, and there was no difference in serious adverse events.
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Treating Preclinical Alzheimer’s Disease
After studying an anti-amyloid antibody, solanezumab, researchers reported there was no benefit in reducing the likelihood of progression of cognitive impairment in patients with positive amyloid PET scans who started the trial cognitively unimpaired, compared to placebo.
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Turmeric (Curcumin) Helps Patients with Dyspepsia and Acid Reflux
In a randomized, controlled trial, curcumin demonstrated comparable efficacy to omeprazole in treating dyspepsia and acid reflux.
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Tachycardia in the Emergency Department: Part II
This issue completes the two-part series on tachycardia. This issue will finish the discussion of additional causes of tachycardia, address management, and conclude by covering some challenging issues with this arrhythmia.
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Chronic Obstructive Pulmonary Disease Update for Primary Care Providers
The Global Initiative for Chronic Obstructive Lung Disease 2023 report defines chronic obstructive pulmonary disease (COPD) as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production, and/or exacerbations) caused by abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that result in persistent, often progressive, airflow obstruction. COPD was the fourth leading cause of death in the United States in 2018 and is estimated to be responsible for 3 million deaths annually around the world, with expected increases to 5.4 million annual deaths from COPD and related conditions by 2060.
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Pediatric Hernias: Diagnosis and Management
Hernias are a common condition encountered by emergency providers and can be overlooked if the genitourinary system is not included in the evaluation of every child with vomiting or abdominal pain. Incarcerated hernias that are not identified in a timely fashion can have devastating consequences for a child. The authors provide an anatomical review, along with diagnostic and therapeutic approaches to pediatric hernias.